Thanks for the information provided to the Illustrator team.
We are able to reproduce this issue at our end and the engineering team is currently isolating this issue further to get to the root cause.
With Best Regards,
An error occurred while saving the commentRichard Schletty commented
Illustrator 2020's hand tool could not be invoked with spacebar today. This has happened before. Previously caused by my 1Password extension running in Chrome. When I deactivated the 1Password extension or quit Chrome, the hand tool could be made to appear using spacebar. AgileBits may have squashed the bug – it hadn't happened to me in over a year.
Today, I discovered that the BitWarden desktop password manager which I am trying out is causing the same inablity to bring up the Illustrator hand tool using spacebar. As soon as I quit BitWarden, spacebar functionality was restored.