Please refer to this KB doc for a solution to this issue – https://helpx.adobe.com/illustrator/kb/wacom-tablet-issue-with-mac.html
Please reach out email@example.com with system info and a screen recording if the above solution did not help
An error occurred while saving the commentJQ commented
I'm experiencing the same issue. I've tried the suggestions below and went through Wacom's entire troubleshooting list, and I just got off the phone with Wacom support and went through that whole procedure with them. This appears to be an Adobe Illustrator issue (and I have pressure recognition in Photoshop). I'm running Illustrator 24.0.1 on OS 10.14.6. Tablet is an Intuos 4 (PTK-640) with the current driver, 6.3.38-2.