Hi there, here is my issue what i found.

Create new file, start working - illustrator is little bit slow. In Preferencies i switch on GPU - everything works perfect. After work i close Illustrator app. Next launch I see the home screen but everytime if I want to open new file or file I was working on before Illustrator freeze and does not work.
Only working solution for this issue is from home screen go to preferencies switch GPU of - open document - switch GPU ON and after that I can continue on my work.

My HW configuration: MSI Prestige P75 9SE, Intel Core i7 9th gen, NVIDIA GeForce RTX 2060, Windows 10 Pro, RAM 16GB