This works:
(tried a few things based on other sites/threads).

Save your work, close all Adobe apps
(didn't work for just Illustrator. I had to close Photoshop and InDesign to make it work)

Option + Click-Finder (in Dock): Relaunch
(Takes just a few seconds)

Opened Illustrator again and problem was solved.

Some threads also said they had to restart computer and issue was fixed. Mine worked just doing the Relaunch Finder thing.

FYI: I'm still running an older CS 5.1 but from my understanding, it's the same issue with the apps running, any version, even CC.

One helper said this issue happens at random times from using the Command + H (hide) in any of the apps. I know this or something similar has happened to me in the past but I've been a designer using Adobe products since 1990 and it's very rare to me.

Hope this helps someone 🙂

Same issue here, CC 2021, MBP2019 touch bar, @Ken High solution it's the only solution ahead

I have this issue every day, multiple times when working!! I can find no pattern to it, but with the zoom tool chosen I press and hold the alt key to switch to zooming out - but instead I get the hand tool! Clicking around, switching tools a couple of times or moving an object often gives me back the functionality again... for a couple of minutes. Please fix this. I pay premium money for this application and bugs like this is so frustrating.

Been having this issue for months now as well. Followed the put the MAC to sleep advice, reawake, and it works again. Great to know this as I hate restarting my computer and losing all that was open including all the tabs in my browser.

Same happening to me with a brand new MacBook Pro 16" 2019 while working with the latest Illustrator 2020 version.
It usually happens after my Macbook goes to sleep when I'm away. Whenever I come back the spacebar shortcut stops working and I have to restart the machine.

I am having the same issue in a classroom full of students.

as noted by CG last year, putting my machine to sleep and re-awaking it fixed the problem.

note that my logitech mx master 3 mouse acted differently during this time too. the tracking speed was different (faster). it is back to normal post sleep/re-wake.

I'm suddenly having the same problem. VERY FRUSTRATING, but glad to know it's not just me.

I'm constantly getting this problem! Have to restart my computer several times a day to get the hand in illustrator when I push the **** spaceboard! Get your **** together Adobe. I know it gets harder and harder the bigger you grow, but I long for the simple days 20 years ago when **** just worked.

since the latest update i cannot zoom out!
Im on a windows pc and by holding alt would normally zoom out, however its now giving me the hand logo to move the document! if i wanted that i would click on the hand menu and move the document!
how can we get zoom out working again?

No way Adobe is "unable to reproduce" this issue. Such BS!!! Losing the keyboard shortcuts for zoom and pan happens far to often and randomly for the huge expense paid for these apps. The Illustrator dev team **** well should have the problem not only identified, but a fix for it.

I've encountered the same problem, only to find the input method on my keyboard was set to another language.

It was simply using another character.

I have been plagued with this problem for the last six months. It comes and goes.
Resetting the permissions on your computer will usually correct the problem. A total PAIN!!!

From the Finder menu bar, choose Go > Home. Your home folder opens.
Choose File > Get Info. An Info window for your home folder opens.
If the Sharing & Permissions section at the bottom of the window isn't open, click the triangle in that section to open it.
If the lock at the bottom of the window is closed lock, click the lock and enter an administrator name and password.
Click the action menu , then choose “Apply to enclosed items.” Click OK to confirm the action.

A progress bar appears at the top of the window. When done, restart your Mac. Or choose Apple menu  > Log Out, then log in again.

turning off Siri shortcut in sys prefs worked for me

Check any settings in your antivirus apps. I have to turn on "Pause Secure Keyboard" every time I turn on my computer so I can use the keyboard commands for the zoom tool in any of the CC apps. I use Webroot. Once I do that, I have no problems.

Illustrator 22.1 running on Mac OS High Sierra 10.13.6. As of yesterday, The keyboard command for the zoom and hand tools has stopped working. I tried restarting the program and restarting the entire computer, and that didn't do anything. I also turned off Ask Siri, that didn't so anything either. What's going on, how do i get it back?

I'm on a AMD Ryzen 7 PC running Windows 10, and I'm having this problem too. It seems to clear for a short while when I restart Illustrator, but not for long. I don't run Siri, or any of the other mentioned software. It sure is a frustrating error.

Got it fixed! Followed this solution (https://macintoshhowto.com/osx/illustrator-stuck-hand-tool-high-sierra.html)
• Set off "Enable Ask Siri"
• In Accessibility > Voice Over Off
• In Keyboard > Dictation set to Off
• Sound > Input > Volume all the way down
• Restart

Then, try your aps and they should be working now. Yo can undo all the sounds stuff that you need back on.

I know, crazy combinations of tweaks, but worked for me

Same here. It just happened suddenly. I have restarted the computer and still not working. Ai, Ph and Indesign have the same issue. None of this aps are usable now, and I have deathlines to get thru today

Running MacOS Mojave 10.14.1

This is so frustrating and basically making the software not fit for purpose. Happening in both illustrator and Photoshop CC2019 Running on High Sierra